ARTICLE
TITLE

Advanced oxidation protein products — biological marker of oxidative stress = Zaawansowane produkty utleniania bialek – biologiczne markery stresu oksydacyjnego

SUMMARY

Cwynar Anna, Olszewska-Slonina Dorota, Czerniak Bartosz, Zyla Magdalena. Advanced oxidation protein products — biological marker of oxidative stress = Zaawansowane produkty utleniania bialek – biologiczne markery stresu oksydacyjnego. Journal of Education, Health and Sport. 2016;6(9):597-603. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.155059http://ojs.ukw.edu.pl/index.php/johs/article/view/3885    The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 755 (23.12.2015).755 Journal of Education, Health and Sport eISSN 2391-8306 7© The Author (s) 2016;This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, PolandOpen Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium,provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License(http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercialuse, distribution and reproduction in any medium, provided the work is properly cited.The authors declare that there is no conflict of interests regarding the publication of this paper.Received: 02.09.2016. Revised 24.09.2016. Accepted: 24.09.2016.   Advanced oxidation protein products — biological marker of oxidative stressZaawansowane produkty utleniania bialek – biologiczne markery stresu oksydacyjnegoAnna Cwynar1, Dorota Olszewska-Slonina1, Bartosz Czerniak1, Magdalena Zyla2 1 Katedra Patobiochemii i Chemii Klinicznej, Collegium Medicum w Bydgoszczy2 Katedra Psychiatrii, Collegium Medicum w Bydgoszczy  ABSTRACTAdvanced oxidation protein products (AOPPs) are mostly derivatives of oxidatively modified albumin. The results of many experimental studies confirm intensification of oxidative modifications of proteins and an increase in concentration of advanced oxidation protein products (AOPPs) in different pathological conditions, particularly those with well documented involvement of oxidative stress in their etiopathogenesis, but also those where its role is not yet well understood. Currently intensive research is carried out on the possibility of using AOPPs as useful indicators for diagnosing, prognosis and monitoring of diseases. Keywords: advanced oxidation protein products, autoimmune disease, oxidative stress STRESZCZENIE Zaawansowane produkty utleniania bialek (AOPPs), to najczesciej pochodne zmodyfikowanej oksydacyjnie albuminy. Wyniki licznych badan doswiadczalnych potwierdzaja nasilenie oksydacyjnych modyfikacji bialek i wzrost stezenia zaawansowanych produktów utleniania bialek (AOPPs) w róznych stanach patologicznych, szczególnie tych o dobrze udokumentowanym udziale stresu oksydacyjnego w ich etiopatogenezie, ale takze takich, w których jego rola nie jest jeszcze dobrze poznana.. Obecnie trwaja intensywne badania nad mozliwoscia wykorzystania AOPPs, jako uzytecznych wskazników do diagnozowania, prognozowania oraz monitorowania chorób. Slowa kluczowe: zaawansowane produkty utleniania bialek, choroby autoimmunologiczne, stres oksydacyjny

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