Home  /  News Of Farmacy  /  Núm: 4 Par: PP (2014)  /  Article
ARTICLE
TITLE

The study of toxicological properties of a new combined cream “Dermalipoin”

SUMMARY

The aim of the work was to study acute toxicity, the irritating and allergic effects of a new combined cream “Dermalipoin” consisting of a-lipoic acid, urea, olive oil, tea tree oil, PEG-400. It has been found that the LD50 of the cream with intragastric introduction is greater than 5000 mg/kg, and when applied to the skin LD50 > 2810 mg/kg; in accordance with the classification of K.K.Sidorov it allows to refer this cream to the class of almost nontoxic substances (the V-th toxicity class). “Dermalipoin” cream shows no irritative action in contact with the mucous membrane of the eye and sensitizing actions in external application.

 Articles related

Shawn Tomy,Ujwala TK,Sandra Celine,C Senthil Kumar,Sam Johnson Udaya Chander J    

Context and Purpose of the Study: DiaKure is a hypoglycemic polyherbal formulation prepared indigenously based on knowledge of traditional medical practitioners, which contains polyherbal mixture of Vetiveria zizanioides (root), Hemidesmus indicus (rhizo... see more


Acharya BalKrishna,Hemanth Kumar Manikyam,Vinay K Sharma,Niti Sharma    

Paris polyphylla Smith is regarded as “Wonder Herb” due to its vast therapeutic applications ranging from diarrhea to cancer. The cytotoxic effect of the rhizome extract on the healthy rats was monitored over a period of time. The extract proved non cyto... see more


Mariana Matias ,Samuel Silvestre ,Amílcar Falcão ,Gilberto Alves    

Purpose - During the discovery and development of new drugs, compounds with low aqueous solubility pose special challenges in their pharmacological evaluation and, therefore, the selection of appropriate vehicles to administer the compounds of interest i... see more


Esti Mulatsari, Yati Sumiyati, Warni Warni    

Averrhoa bilimbi L. is generally used as a food flavor enhancer and traditional medicine to treat inflammation, cancer sores, cough, fever, gout, rectal bleeding, and hemorrhoids. In vivo and invitro studies on Averrhoa bilimbi L. have shown anti-inflamm... see more


V. L. Karbovsky, I. A. Shevchuk, T. Ye. Makovska, O. A. Makovskyi    

RESEARCH ON ACUTE TOXICITY "CHONDROSUT" DRUGV. L. Karbovsky1, I. A. Shevchuk1, T. Ye. Makovska2, O. A. Makovskyi1LLC «Biofarma», Bila Tserkva1,Main Military Medical Hospital, Kyiv2Introduction. One of the most common locomotor system disease that is suff... see more