SUMMARY
The article is devoted to substantiation of the theoretical aspects of management decision, its modern methods and adaptation of classical theories to pharmaceutical management. The efficiency of enterprises depends on the level of the enterprise management organization and decision-making efficiency. Most management decisions are made under uncertainty, which causes risk in the organizations activity. Each problem of decision-making is different. Some initial situation, alternative solutions, implications of different options are common to all the problems. With these components any problem decision can be described. The requirements for effective management decisions have been analyzed. The algorithm for management decision making when applying different types of management at the enterprise.