Home  /  News Of Farmacy  /  Núm: 4 Par: PP (2015)  /  Article
ARTICLE
TITLE

The antibacterial and antifungal action of copper nanoparticles in vitro in relation to pathogenic test strains and clinical isolates of microorganisms – causative agents of infectious and inflammatory processes of different localization

SUMMARY

The results of determination of the antibacterial and antifungal action of 20 nm copper nanoparticles obtained according to the original protocol by the method of chemical condensation in the aqueous solution in relation to the broad spectrum of pathogenic test strains such as Staphylococcus aureus MRSA ATCC 43300, Escherichia coli ATCC 2592, Pseudomonas aeruginosa ATCC 27853, S. aureus 209P, Salmonella typhimurium 144, Shigella sonnei and Candida albicans, in testing sensitivity by the method of serial dilution in agar with the doses of microorganisms of 103-105 CFU/cm3 are presented in the article. Copper nanoparticles have shown the antibacterial and antifungal action on clinical isolates of causative agents of infectious and inflammatory processes of different localization isolated from surgical patients, such as S. aureus, E. coli, Proteus mirabilis, Klebsiella pneumoniae, Enterobacter aerogenes, P. aeruginosa, C. albicans, Candida non-albicans, Penicillium spp., Paecilomyces lilacinus, Aspergillus niger, and Aspergillus flavus, in testing sensitivity by the method of dosed drops with the dose for each microorganism of 107 CFU/cm3.

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