Selected Abstracts of the 2nd Congress of joint European Neonatal Societies (jENS 2017); Venice (Italy); October 31-November 4, 2017; Session "Neurology and Follow-up"

SUMMARY

58th ESPR Annual Meeting, 7th International Congress of UENPS, 3rd International Congress of EFCNIORGANIZING INSTITUTIONSEuropean Society for Paediatric Research (ESPR), European Society for Neonatology (ESN), Union of European Neonatal & Perinatal Societies (UENPS), European Foundation for the Care of Newborn Infants (EFCNI)ORGANIZING COMMITTEELuc Zimmermann (President of ESPR), Morten Breindahl (President of ESN), Manuel Sánchez Luna (President of UENPS), Silke Mader (Chairwoman of the Executive Board and Co-Founder of EFCNI)SCIENTIFIC COMMITTEEVirgilio P. Carnielli (Congress President Chair), Pierre Gressens (Past Scientific President), Umberto Simeoni, Manon Benders, Neil Marlow, Ola D. Saugstad, Petra Hüppi, Agnes van den HoogenABS 1. PRETERM BIRTH AND THE TIMING OF PUBERTY • E. James, C. Wood, H. Nair, T. WilliamsABS 2. NEONATAL PAIN, OPIOID AND ANAESTHETIC EXPOSURE; WHAT REMAINS IN THE HUMAN BRAIN AFTER THE WHEELS OF TIME? • G.E. van den Bosch, D. Tibboel, J.C. de Graaff, H. El Marroun, A. van der Lugt, T. White, M. van DijkABS 3. DEPRESSION DURING PREGNANCY AND DNA METHYLATION CHANGES IN CORD BLOOD • A.-C. Viuff, G. Sharp, D. Raj, K.J. Kyng, L.H. Pedersen, T.B. Henriksen, C.L. ReltonABS 4. PREVENTION OF CEREBRAL PALSY: FEASIBILITY OF UMBILICAL CORD BLOOD STEM CELLS AND UMBILICAL CORD MESENCHYMAL STROMAL CELLS • H. Shintaku, M. Nabetani, T. Hamazaki, S. Kusuda, M. Tamura, S. Watabe, M. Hayakawa, Y. Sato, M. Tsuji, A. Taguchi, H. Ichiba, O. Akira, R. Mori, A.Taki, T. Mukai, T. Nagamura-InoueABS 5. NO GENDER-RELATED DIFFERENCES IN FETAL CORPUS CALLOSUM THICKNESS: IN-UTERO MRI STUDY • R. Bercovitz, R. Achiron, C. Hoffmann, A. AchironABS 6. NEUROMOTOR PROFILE OF HIGH-RISK INFANTS AT TERM OR NEAR TERM • I. Ereno, W.Y. TehABS 7. THE PREDICTIVE VALUE OF SEVERE BRONCHOPULMONARY DYSPLASIA FOR NEUROLOGICAL IMPAIRMENT IN 2-YEARS-OLD VERY PRETERM INFANTS IS HIGHER WHEN DIAGNOSED AT 40 THAN AT 36 WEEKS’ POSTMENSTRUAL WEEKS • A.M. Malavolti, D. Bassler, R. Arlettaz-Mieth, G. Faldella, B. Latal, G. NatalucciABS 8. PSYCHOSOCIAL OUTCOME OF INFANTS WITH CONGENITAL MALFORMATIONS AFTER POSTNATAL SURGICAL REPAIR • N. Doberschuetz, A. Allendorf, R. Dewitz, B. Wittekindt, U. Rolle, R. SchloesserABS 9. THERAPEUTIC HYPOTHERMIA AND HEARING IMPAIRMENT: INCIDENCE AND ASSOCIATED FACTORS • M.P. Fitzgerald, G. Norman, C. Mc Garvey, A. Reynolds, M. King, B. HayesABS 10. PRETERM INFANTS 33-35 WEEKS’ GESTATION WITH SEVERE HYPOXIC-ISCHEMIC ENCEPHALOPATHY TREATED WITH HYPOTHERMIA DO NOT PRESENT MORE ORGAN DYSFUNCTION THAN TERM NEWBORNS • M. Alsina, A. Martin-Ancel, M. Leon, G. Arca, E. Perez, A. García-AlixABS 11. IMPACT OF ENVIRONMENTAL FACTORS ON MOTOR AND COGNITIVE PERFORMANCE OF LATE PRETERM INFANTS • M.M. Santos, C. Corsi, A.C. Campos, N.A.C.F. RochaABS 12. THROMBOCYTOPENIA IS ASSOCIATED WITH SEVERE RETINOPATHY OF PREMATURITY CLINICALLY; IN MICE PLATELET TRANSFUSION SUPPRESSES RETINOPATHY • P. Lundgren, R. Liegl, S. Klevebro, G. Hellgren, C. Löfqvist, C. Mannheimer, Y. Sun, Z.-J. Liu, M.C. Sola-Visner, B. Hallberg, L.E.H. Smith, A. HellströmABS 13. COGNITIVE AND BEHAVIORAL ASPECTS OF EXECUTIVE FUNCTIONING AT AGE 6.5 YEARS IN CHILDREN BORN EXTREMELY PRETERM: A SWEDISH NATIONAL PROSPECTIVE STUDY (EXPRESS) • A. Farooqi, F. Serenius, M. Adamsson, M. Hafström, U. Åden, K. StjernqvistABS 14. EARLY AMPLITUDE INTEGRATED ELECTRO­ENCEPHALOGRAM AS A PREDICTOR OF BRAIN INJURY IN NEWBORNS WITH VERY LOW BIRTH WEIGHT: A COHORT STUDY • R.C. Silveira, L.V. Magalhaes, M.I. Winckler, J.A. Bragatti, R.S. ProcianoyABS 15. NEONATAL ADMISSIONS FOR HYPOXIC ISCHEMIC ENCEPHALOPATHY: WEEKEND AND OUT OF HOURS EFFECT • F. Ceroni, M. Parmar, S. Narayanan, N. MerchantABS 16. WHICH PARTS OF GROWTH SHOULD BE MONITORED FOR NEURODEVELOPMENT OF PRETERM INFANTS • I.G. Song, H.R. Yoon, Y.M. Yoon, J.S. Shin, S.H. Shin, E.K. Kim, H.S. KimABS 17. TARGETED METHYLATION TESTING OF A 154 PATIENT’S COHORT WITH CLINICAL FEATURES OF IMPRINTING DISORDERS: EVIDENCE OF MULTILOCUS METHYLATION DEFECTS • A.Touati, S. Nouri, F. Chioukh, M. Haddaji Mastouri, N. Ben Salah, S. Trabelsi, S. Hammami, S. Mougou, M. Gribaa, N. Guedich, H. Seboui, A. Nouri, K. Monastiri, A. Saad, D. H’mida-Ben BrahimABS 18. STEINERT MYOTONIC DYSTROPHY (DM1): WHAT ABOUT CARDIAC INVOLVEMENT? • H. Hadj Abdallah, Y. Halleb, N. Ben Salah, F.Z. Chioukh, K. Ben Ameur, F. Kallel, L. Ben Slamia, S. Hidar, M. Bellallah, S. Nouri, S. Ben Amor, A. Hsin, M. Grira, H. Ajmi, S. Zardi, S. Abroug, N. Mahdhaoui, H. Sboui, S. Ben Ammou, K. Mestiri, A. Saad, D. H’midaABS 19. ATYPICAL BRAIN DEVELOPMENT ASSOCIATED WITH PRENATAL METHADONE EXPOSURE • V. Monnelly, D. Anblagan, A. Quigley, E. Cooper, H. Mactier, S. Semple, M. Bastin, J. BoardmanABS 20. CHARACTERISATION OF THE NEONATAL CORPUS CALLOSUM (CC) USING MAGNETIC RESONANCE IMAGING (MRI) AND CRANIAL ULTRASOUND (US) • M. Mills, V. Pelling, L. Harris, J. Smith, H. Rabe, R. FernandezABS 21. COGNITIVE TRAJECTORIES FROM INFANCY TO EARLY ADULTHOOD FOLLOWING BIRTH BEFORE 26 WEEKS OF GESTATION • L. Linsell, S. Johnson, D. Wolke, H. O’Reilly, J. Morris, J. Kurinczuk, N. MarlowABS 22. INHIBITORY CONTROL AT 20 MONTHS PRE­DICTS VP/VLBW AND TERM ADULTS’ ATTEN­TION, IQ, AND WEALTH AT AGE 26 YEARS • J. Jaekel, N. Baumann, P. Bartmann, D. WolkeABS 23. HEAD MIDLINE POSITION FOR THE PREVEN­TION OF GERMINAL MATRIX-INTRAVENTRICU­LAR HEMORRHAGE IN PRETERM INFANTS: A SYSTEMATIC REVIEW AND META-ANALYSIS • O. Romantsik, M.G. Calevo, M. BruschettiniABS 24. MOTOR FUNCTION AT EARLY SCHOOL AGE IN EXTREMELY PRETERM BORN CHILDREN WITHOUT MAJOR IMPAIRMENTS IN RELATION TO PERINATAL FACTORS: NATIONAL POPULATION-BASED STUDY (EXPRESS) • J. Bolk, A. Farooqi, M. Hafström, U. Åden, F. SereniusABS 25. COGNITIVE FUNCTIONING IN ADOLESCENTS BORN MODERATELY PRETERM AT 32-26 WEEKS’ GESTATION: A SWEDISH REGIONAL POPULATION BASED CASE CONTROL STUDY • M. Adamsson, B. Hägglöf, M. Bäckman, A. FarooqiABS 26. EARLY RISK FACTORS FOR ADVERSE NEUROMOTOR DEVELOPMENT IN TERM INFANTS AFTER MODERATE HYPOXIC-ISCHAEMIC ENCEPHALOPATHY • A. MaticABS 27. THERAPEUTIC HYPOTHERMIA IN BABIES WITH HYPOXIC-ISCHAEMIC ENCEPHALOPA­THY: EVIDENCE AND CLINICAL PRACTICE • K. Ghazal, A. Panickar, S. GargABS 28. EFFECT OF DEHYDROEPIANDROSTERONE AND ITS SULFATE ESTER ON NEONATAL HYPOXIC-ISCHEMIC BRAIN INJURY – PRELIMINARY DATA • A. Posod, M. Lachinger, B. Vejnoska, E. Huber, M. Urbanek, U. Kiechl-Kohlendorfer, E. GriesmaierABS 29. LONG-TERM EFFECTS OF NEONATAL COMPLICATIONS ON BRAIN GROWTH AT 10 YEARS OF AGE IN CHILDREN BORN EXTREMELY PRETERM • N. Padilla, C. Jimenez-Espinoza, H. Kvanta, U. AdénABS 30. SECRETONEURIN SERUM CONCENTRATIONS CORRELATE WITH ABNORMAL NEURODEVELOPMENTAL OUTCOME AT THE AGE OF 24 MONTHS IN TERM NEONATES WITH ASPHYXIA • K. Wechselberger, A. Schmid, M. Höck, A. Posod, M. Urbanek, R. Fischer-Colbrie, V. Neubauer, U. Kiechl-Kohlendorfer, E. GriesmaierABS 31. SCREENING C677T POLYMORPHISM IN METHYLENETETRAHYDROFOLATE REDUCTASE GENE IN TAIWAN POPULATION • C.Y. Chuang, C.C. Hung, Y.N. Su, P.N. TsaoABS 32. GENETIC CONTRIBUTIONS TO THE DEVELOPMENT OF INTRAVENTRICULAR HEMORRHAGE IN PRETERM NEWBORNS • D. Szpecht, J. Gadzinowski, A. Seremak-Mrozikiewicz, G. Kurzawinska, K. Drews, M. SzymankiewiczABS 33. MRI-DIAGNOSED WHITE MATTER LESIONS IN THE BRAIN OF VLBW BABIES: RISK FACTOR ANALYSIS • A. Parodi, S. Raffa, M. Malova, A. Sannia, M. Severino, G. Morana, D. Tortora, M.G. Calevo, A. Rossi, L.A. RamenghiABS 34. A NEW EVALUATION INDEX FOR LEFT-RIGHT UNEQUAL VENTRICULOMEGALY IN VERY LOW BIRTH WEIGHT INFANTS: ASSOCIATION WITH WALKING DISABILITIES AT 1.6 YEARS OF CORRECTED AGE • T. Ikuta, M. Mizobuchi, Y. Katayama, S. Yoshimoto, T. Ioroi, M. Yamane, T. Morisawa, A. Takatera, M. Ueda, A. Shibata, K. Maeyama, K. Fujioka, N. Nishimura, K. Iijima, I. MoriokaABS 35. EPIGENETIC DIFFERENCES IN CORD BLOOD OF NEWBORNS EXPOSED TO ANTIDEPRESSANT MEDICATION DURING PREGNANCY – A STUDY IN THE AARHUS BIRTH COHORT • A.-C. Viuff, G.C. Sharp, L.H. Pedersen, N.H. Staunstrup, K.J. Kyng, D. Rai, C.L. Relton, T.B. HenriksenABS 36. AUTISM SPECTRUM DISORDER IN EX-PRETERMS IS PRECEDED BY ALTERED NEONATAL BRAIN VOLUMES IN MULTIMODAL ASSOCIATION AREAS AND ALTERED PATTERNS OF BRAIN ASYMMETRY • N. Padilla, E. Eklöf, G. Mårtensson, S. Bölte, H. Lagercrantz, U. ÅdenABS 37. COGNITIVE OUTCOME IN ADULTS BORN WITH VERY LOW BIRTH WEIGHT OR SMALL FOR GESTATIONAL AGE • S. Weider, A.M.W. Lærum, K.A.I. Evensen, S. Lydersen, A.M. Brubakk, M.S. IndredavikABS 38. PERFORMANCE OF THE GERMAN VERSION OF THE PARCA-R QUESTIONNAIRE AS A COGNITIVE SCREENING TOOL IN VERY PRETERM INFANTS AT 2 YEARS OF CORRECTED AGE • G. Natalucci, N. Bechtel, C. Borradori-Tolsa, M. Bickle-Graz, M. Adams, S. Grunt for the Swiss Neonatal Network & Follow-Up GroupABS 39. NEURODEVELOPMENT IN 7-YEAR OLD CHILDREN BORN WITH MARGINALLY LOW BIRTH WEIGHT • J. Starnberg, M. Norman, B. Westrup, M. Domellöf, S.K. BerglundABS 40. EARLY NEONATAL EEG MARKERS FOR DYSLEXIA RISK: A PILOT STUDY • S. Martini, P. Cyr, L. Brightman, L. Amunts, G. Belteki, T. Austin, V. LeongABS 41. MATERNAL SWIMMING DURING PREGNANCY PROTECTS THE NEONATAL RAT BRAIN FROM HYPOXIC-ISCHEMIC INJURY • E.F. Sanches, Y. van de Looij, A. Silva, J. Romero, S.V. SizonenkoABS 42. PERSISTENT MATHEMATICS LEARNING DIFFICULTIES FROM CHILDHOOD TO ADOLESCENCE IN VERY PRETERM CHILDREN IN MAINSTREAM SCHOOL • S. Clayton, L. Cragg, C. Gilmore, N. Marlow, V. Simms, R. Spong, S. JohnsonABS 43. PRENATAL METHADONE EXPOSURE AND NEURODEVELOPMENTAL AND NEURO­IMAGING OUTCOMES: A SYSTEMATIC REVIEW • V. Monnelly, R. Hamilton, F. Chappell, H. Mactier, J. BoardmanABS 44. NEURODEVELOPMENT FOLLOW-UP FOR HIGH-RISK BABIES IN LIVERPOOL: A QUALITATIVE STUDY. FOUNDATION STUDY “FOLLOW-UP FOR NEURODEVELOPMENTALLY AT RISK INFANTS OF NEONATAL CARE” • A. Komoriyama, F. Paize, C. Dewhurst, M. GladstoneABS 45. COLD-INDUCIBLE RBM3 PROMOTES NEUROGENESIS AFTER BRAIN HYPOXIC-ISCHEMIA/REPERFUSION INJURY • X. Zhu, C. Brégère, J. Yan, U. Fisch, J. Kapfhammer, R. Guzman, S. WellmannABS 46. REACHING SKILLS OF INFANTS BORN VERY PRETERM PREDICT NEURODEVELOPMENT AT 3 YEARS • Y. Fredriksson Kaul, K. Rosander, H. Grönqvist, K. Strand Brodd, L. Hellström-Westas, C. von HofstenABS 47. RETINOPATHY OF PREMATURITY AND NEUROCOGNITIVE FUNCTION AT AGE 10 IN CHILDREN BORN EXTREMELY PRETERM • M. Holm, T.S. Morken, R.M. Joseph, M.E. Msall, T.M. ÓShea, K.C.K. Kuban, O. Dammann, E.N. Allred, A. LevitonABS 48. UNDERSTANDING ADHD AND ASD IN VERY PRETERM CHILDREN FROM A SENSORY PROCESSING PERSPECTIVE: A CONTROLLED NEUROPSYCHOLOGICAL STUDY • T. Bröring, K. Oostrom, M. Königs, E. van Dijk-Lokkart, H. Lafeber, A. Brugman, J. OosterlaanABS 49. SOCIAL-EMOTIONAL DEVELOPMENT IN VERY PRETERM INFANTS DURING EARLY INFANCY • P.H. Gray, D.M. Edwards, M. PritchardABS 50. TOUCHSCREENS FOR COGNITIVE ASSESSMENT OF TODDLERS • D.M. Twomey, C. Wrigley, C. Ahearne, R. Murphy, M. de Haan, N. Marlow, D.M. MurrayABS 51. NEUROPROTECTIVE INTERVENTION AFTER HYPOXIA-ISCHEMIA MAY CHANGE INTRACEREBRAL METABOLIC MEASURES IN A NEWBORN PIGLET MODEL • T.C. Andelius, N. Bøgh, M.V. Pedersen, C. Omann, V.E. Hjortdal, M. Pedersen, T.B. Henriksen, K.J. KyngABS 52. TWO-YEAR OUTCOME OF EXTREMELY PRETERM INFANTS < 26 WEEKS OF GESTATION BORN IN SWITZERLAND: IS INTENSITY OF PERINATAL CARE ASSOCIATED WITH INCREASED NEURODEVELOPMENTAL IMPAIRMENT? • G. Natalucci, T.M. Berger, C. Borradori-Tolsa, M. Bickle-Graz, S. Grunt, R. Gerull, D. Bassler, M. Adams for the Swiss Neonatal Network & Follow-Up GroupABS 53. SELF-REPORTED WIDESPREAD PAIN IN ADULTS BORN EARLY AND LATE PRETERM • K.A.I. Evensen, M. Tikanmäki, K. Heinonen, H.-M. Matinolli, M. Sipola-Leppänen, A. Lano, D. Wolke, M. Vääräsmäki, J.G. Eriksson, S. Andersson, M.-R. Järvelin, P. Hovi, K. Räikkönen, E. KajantieABS 54. BRAIN VOLUMES BY CEREBRAL MRI AND CORRELATIONS WITH PSYCHIATRIC SYMPTOMS IN LOW BIRTHWEIGHT ADULTS • A.M.W. Lærum, L.M. Rimol, S.K. Reitan, A. Brubakk, K.A.I. Evensen, K.J. Bjuland, S. Lydersen, J. Skranes, M.S. IndredavikABS 55. POSTURE AND MOBILITY INFLUENCE ON ATTENTION ABILITIES IN HEALTHY 7 YEARS OLD CHILDREN • H. Ceyte, J. Rosenbaum, S. Caudron, J.-M. HascoetABS 56. SURGICAL DECISION MANAGEMENT IN CHIARI TYPE 2 MALFORMATION: A SINGLE CENTER EXPERIENCE • S.A. Ozdemir, N. Ozdemir, A. Karadag, E.A. OzerABS 57. EFFECTS OF NEURAL STEM CELL MEDIA ON HYPOXIC INJURY IN RAT HIPPOCAMPAL SLICE CULTURES • N.M. Lee, S.A. Chae, H.J. LeeABS 58. A NOVEL CEREBRAL ULTRASOUND SCORING SYSTEM IS ASSOCIATED WITH NEURO­LOGICAL OUTCOME IN NEONATES WITH HYPOXIC-ISCHEMIC ENCEPHALOPATHY • K. Annink, F. Groenendaal, M. Lequin, D. Vijlbrief, L. de Vries, M. Benders, J. DudinkABS 59. MONITORING THE ENERGY METABOLISM IN PLASMA FROM NEWBORNS WITH HYPOXIC-ISCHEMIC ENCEPHALOPATHY (HIE) DURING THERAPEUTIC HYPOTHERMIA • Á. Sánchez-Illana, A. Núñez-Ramiro, M. Cernada, A. Parra, E. Valverde, D. Blanco, M.T. Moral-Pumarega, F. Cabañas, H. Boix, A. Pavon, M. Chaffanel, I. Benavente-Fernández, I. Tofe, B. Loureiro, J.R. Fernández-Lorenzo, B. Fernández-Colomer, J. Kuligowski, M. Vento; the HYPOTOP Study GroupABS 60. PHOSPHOLIPID SYNTHESIS RELATED BIOMARKERS IN PLASMA FROM NEWBORNS WITH HYPOXIC-ISCHEMIC ENCEPHALOPATHY • J. Kuligowski, Á. Sánchez-Illana, J.D. Piñeiro-Ramos, A. Núñez-Ramiro, M. Cernada, A. Parra, E. Valverde, D. Blanco, M.T. Moral-Pumarega, F. Cabañas, H. Boix, A. Pavon, M. Chaffanel, I. Benavente-Fernández, I. Tofe, B. Loureiro, J.R. Fernández-Lorenzo, B. Fernández-Colomer, M. Vento; the HYPOTOP Study GroupABS 61. CEREBROSPINAL FLUID LACTATE IN NEWBORN AND PRETERM INFANTS. PILOT DATA • G. Uclés, D. Arjona, R. Borrego, R. Díaz, M.D. Sánchez-Redondo, A. EscobarABS 62. DIFFERENCES BETWEEN INTRAUTERINE AND EXTRAUTERINE GROWTH OF THE CEREBELLUM • A.I. Toma, I. Cuzino, A. Cozinov, R.G. OlteanuABS 63. CAN DIFFERENCES IN EARLY FUNCTIONAL CONNECTIVITY IN HEALTHY NEWBORNS EXPOSED TO OLFACTORY STIMULATION HELP US UNDERSTAND CRYING BEHAVIOUR AT 6 WEEKS OF LIFE? • L. Freitas, A. Adam-Darque, F. Grouiller, J. Sauser, F. Lazeyras, P. Pollien, C.L. Garcia-Rodenas, G. Bergonzelli Degonda, D. Van De Ville, P. Hüppi, R. Ha-Vinh LeuchterABS 64. LESS INVASIVE SURFACTANT ADMINISTRA­TION (LISA) NOT ONLY IMPROVES MORTALITY AND MORBIDITY BUT ALSO NEURO­DEVELOP­MENTAL OUTCOME OF PRETERM INFANTS • K. Klebermass-Schrehof, A. Grill, M. Hayde, N. Haiden, A. Flunt, R. Fuiko, S. Brandstetter, A. BergerABS 65. REDUCED PREVALENCE OF SEVERE INTRA­VENTRICULAR HEMORRHAGE IN VERY PRE­TERM INFANTS DELIVERED AFTER MATERNAL PREECLAMPSIA • E. Morsing, K. Maršál, D. LeyABS 66. COGNITIVE STABILITY IN CHILDREN WITH CONGENITAL HEART DISEASE • N. Naef, C. Schaefer, V. Rousson, R. Liamlahi, S. Polentarutti, I. Beck, V. Bernet, H. Dave, W. Knirsch, B. LatalABS 67. PERIPHERAL T CELL DEPLETION BY FINGOLI­MOD IS ASSOCIATED WITH EXACERBATED HYPOXIC-ISCHEMIC BRAIN INJURY IN NEO­NATAL MICE • I. Bendix, M. Crasmöller, C. Köster, M. Serdar, U. Felderhoff-Müser, J. HerzABS 68. DIFFERENTIATING THE PRETERM PHENO­TYPE: DISTINCT PROFILES OF DEVELOP­MENT AF­TER LATE AND MODERATELY PRETERM BIRTH • S. Johnson, G. Waheed, B.N. Manktelow, D. Field, N. Marlow, E.S. Draper, E.M. BoyleABS 69. NEONATAL NEUROIMAGING IN SYMPTOMATIC CONGENITAL CMV (cCMV) AND ITS CORRELATION WITH OUTCOME: EMPHASIS ON WHITE MATTER DISEASE • A. Alarcon, A. Garcia-Alix, M. Martinez-Biarge, I. van Straaten, F. Cabañas, J. Quero, L. de VriesABS 70. INTRANASALLY APPLIED MESENCHYMAL STEM CELLS MIGRATE TO INJURED BRAIN REGIONS OF NEWBORN NON-HUMAN PRIMATES • N. Wagenaar, F. van Bel, M. Benders, C. Blanco, D. McCurmin, S. Mustafa, F. Groenendaal, L. de Vries, C. Heijnen, C. NijboerABS 71. EARLY CRANIAL ULTRASOUND AND MRI AT TERM IN VERY PRETERM INFANTS: DIAGNOSIS OF BRAIN INJURY VERSUS NEURODEVELOPMENTAL OUTCOME AT 12 AND 24 MONTHS CORRECTED GESTATIONAL AGE • K. Chatzidimitriou, A. Chebsey, D. Odd, M. El Brookle, M. Likeman, A. HeepABS 72. CRANIAL ULTRASOUND AT DAY 7 AND CLINICAL MRI AT TERM IN VERY PRETERM INFANTS BORN AT LESS THAN 28 WEEKS: VENTRICULOMEGALY IS RELATED TO SUBTLE BRAIN PATHOLOGY AND UNFAVORABLE DEVELOPMENTAL OUTCOME AT 24 MONTH • K. Chatzidimitriou, A. Chebsey, D. Odd, M. El Brookle, M. Likeman, A. HeepABS 73. AUTOPHAGY INHIBITION PROTECTS IN A PRETERM RAT MODEL OF EXCITOTOXIC BRAIN INJURY • C. Descloux, V. Ginet, J. Puyal, A.C. TruttmannABS 74. VALIDITY OF THE KOREAN DEVELOPMENTAL SCREENING TEST FOR VERY LOW BIRTH WEIGHT INFANTS • C.Y. Kim, J.H. Hwang, E. Jung, B.S. Lee, K.S. Kim, A.R. KimABS 75. INTERACTION BETWEEN ACUTE THERA­PEU­TIC HYPOTHERMIA AND A DELAYED MES­ENCHYMAL STEM CELL THERAPY IN NEO­NATAL HYPOXIA-ISCHEMIA • J. Herz, C. Köster, B.S. Reinboth, M. Dzietko, I. Bendix, U. Felderhoff-MüserABS 76. IMPACT OF NEONATAL WHITE MATTER INJURY AND BRAIN VOLUMES TO SCHOOL-AGE NEURODEVELOPMENT IN CHILDREN WITH CONGENITAL HEART DISEASE • N.H.P. Claessens, S.O. Algra, T.L. Ouwehand, N.J.G. Jansen, P. Moeskops, I. Išgum, R. Schappin, I.C. van Haastert, M.J.C. Eijsermans, F. Groenendaal, L.S. de Vries, M.J.N.L. BendersABS 77. ASYNCHRONY AND SPECTRAL EEG COHERENCE IN TERM NEONATES WITH INTRAUTERINE GROW RESTRICTION • B. Reyes Millán, J.R. Castro Conde, C. González Campo, I. Quintero Fuentes, N.L. González González, D. González BarriosABS 78. MUSIC EFFECTS IN PRETERM INFANTS’ BRAIN: A STRUCTURAL NEUROIMAGING INVESTIGATION • J. Almeida, N. Kunz, L. Lordier, A. Darque, F. Lazeyras, P. HüppiABS 79. CONGENITAL HEART DEFECTS AND ACADEMIC PERFORMANCE IN A NATIONWIDE COHORT OF 458,318 DANISH CHILDREN • N.B. Matthiesen, S.H. Larsen, T.B. Henriksen, C.C. Bach, J.R. Ostergaard, V. HjortdalABS 80. PROGNOSTIC VALUE OF EARLY CONVENTIONAL PROTON MAGNETIC RESONANCE SPECTROSCOPY IN COOLED ASPHYXIATED NEWBORNS • H. Barta, A. Jermendy, M. Kolossvary, L.R. Kozak, A. Lakatos, U. Meder, G. Rudas, M. SzaboABS 81. CYTOKINES TRAJECTORIES IN NEWBORNS WITH HYPOXIC-ISCHEMIC ENCEPHALOPATHY: THE ROLE OF HYPOTHERMIA • S. Perrone, S. Cornacchione, M.D. Weiss, R. Candace, M. Longini, F. Proietti, M. Calderisi, G. BuonocoreABS 82. COLD-INDUCIBLE RBM3 AUGMENTS IGF2 EXPRESSION IN NEURAL STEM CELLS BY INTERACTING WITH IMP2 IN AN RNA-DEPENDENT MANNER • J. Yan, X. Zhu, A. Zelmer, J. Kapfhammer, S. WellmannABS 83. EARLY POSTOPERATIVE AMPLITUDE-INTEGRATED ELECTROENCEPHALOGRAPHY: BIOMARKER OF NEW BRAIN INJURY IN NEONATES WITH CONGENITAL HEART DISEASE • N.H.P. Claessens, L. Noorlag, L. Weeke, M. Toet, J.M.P.J. Breur, M.J.N.L. Benders, F. Groenendaal, N.J.G. Jansen, L.S. de VriesABS 84. STABILITY OF AUTISM DIAGNOSIS IN CHILDREN BORN VERY-PRETERM FROM AGE 2 TO 4 YEARS • M. Pritchard, H. Haydon, T. de Dassel, E. Beller, F. Bogossian, L. Johnston, J. Paynter, S. Russo, J.G. ScottABS 85. ASSOCIATION BETWEEN TRANSIENT NEONATAL HYPOGLYCEMIA AND ADVERSE NEUROLOGICAL DEVELOPMENT AT 2-6 YEARS OF AGE • R. Wickström, B. Skiöld, G. Petersson, O. Stephansson, M. AltmanABS 86. PERINATAL ASSOCIATIONS WITH BRAIN GROWTH EVALUATED BY SEQUENTIAL CRANIAL ULTRASONOGRAPHY IN VERY PRETERM INFANTS • R. Cuzzilla, A.J. Spittle, K.J. Lee, S. Rogerson, F.M. Cowan, L.W. Doyle, J.L.Y. CheongABS 87. NEUROFILAMENT SERUM LEVELS AS BIOMARKER OF NEURONAL INJURY IN VERY PRETERM BORN INFANTS • A. Depoorter, C. Barro, R. Neumann, J. Kuhle, S. WellmannABS 88. PREDICTING THE DEVELOPMENT OF CEREBRAL PALSY: A COMPARISON BETWEEN DTI-MRI AND EARLY HAND ASSESSMENT IN INFANTS WITH UNILATERAL PERINATAL BRAIN INJURY • B. van Gasselt, N. Wagenaar, C. Verhage, M. Benders, F. Groenendaal, L. de Vries, N. van der AaABS 89. MICRORNA PANEL VALIDATION IN HYPOXIC ISCHEMIC ENCEPHALOPATHY • M.P. O’Sullivan, A.M. Looney, G. Moloney, B. Hallberg, G. Clarke, G.B. Boylan, D.M. MurrayABS 90. OUTBORN PRETERM INFANTS WITH POST-HAEMORRHAGIC VENTRICULAR DILATATION: ARE THEY TRANSFERRED TOO LATE? • A. Parodi, M. Malova, A. Sannia, A. Cama, M. Ravegnani, C. Bellini, L.A. RamenghiABS 91. CEACAM1 EXPRESSION IN THE CEREBELLUM • S. Prager, B.B. Singer, I. Bendix, J. Herz, U. Felderhoff-MüserABS 92. LONG-TERM NEURODEVELOPMENTAL OUTCOMES AMONG YOUNG ADULTS BORN PRETERM • M. Tei, S. Negro, M.C. Muraca, M.G. Gatti, D. Urilli, G. Buonocore, S. PerroneABS 93. LOW-GRADE IVH AND LOW-GRADE CBH: WHICH INFLUENCE ON GRIFFITHS SCORE AT 2 YEARS OF AGE? • A. Parodi, M. Malova, S. Uccella, L. Boeri, E. De Grandis, A. Sannia, M. Severino, G. Morana, D. Tortora, A. Rossi, E. Veneselli, L.A. RamenghiABS 94. GENETIC CAUSES IN NEWBORNS WITH EPILEPTIC ENCEPHALOPATHIES • A. Soltirovska Salamo, D. Paro-PanjanABS 95. OUTCOME AT FIVE YEARS OLD IN A SWISS NATIONAL COHORT OF VERY PRETERM INFANTS BORN IN 2006 • M.P. Pittet, M. Adams, M. Bickle-Graz, S. Grunt, I. Mürner-Lavanchy, R.E. Pfister, G. Natalucci, C. Borradori TolsaABS 96. PLACENTAL HISTOLOGY FINDINGS AS POSSIBLE RISK FACTORS FOR MRI-DETECTED BRAIN LESIONS IN VLBW INFANTS • A. Parodi, M. Re, D. Brignole, M.P. Brisigotti, M.G. Calevo, M. Malova, A. Sannia, M. Severino, G. Morana, D. Tortora, A. Rossi, E. Fulcheri, L.A. RamenghiABS 97. SYSTEMIC INFLAMMASOME ACTIVATION IN NEONATAL ENCEPHALOPATHY • M. O’Dea, L. Kelly, J.J. O’Leary, E.J. MolloyABS 98. LONGITUDINAL STUDY OF BRAIN TISSUE VOLUMES IN PRETERM INFANTS AND THEIR RELATION WITH NEONATAL RISK FACTORS AND NEURODEVELOPMENTAL OUTCOME • L. Gui, F. Lazeyras, P.S. Hüppi, C. BorradoriABS 99. DELINEATING THE BEHAVIOURAL PHENOTYPE AMONG CHILDREN BORN EXTREMELY PRETERM • J. Trickett, D. Wolke, C. Hollis, N. Marlow, S. JohnsonABS 100. NANOMOLECULAR SIGNALLING IN THE DEVELOPING BRAIN: CHARACTERISTICS OF EXOSOMES IN THE CEREBROSPINAL FLUID OF PRETERM INFANTS • R. Spaull, B. McPherson, A. Clayton, J. Uney, O. Cordero-Llana, A. HeepABS 101. BEDSIDE MONITORING OF CEREBRAL METABOLISM IN NEONATES AT RISK FOR HYPOXIC-ISCHEMIC ENCEPHALOPATHY • M. El-Dib, S.J. Blackwell, F. Yi, R. Vyas, C.G. Ha, B. Walsh, T.E. Inder, P.E. Grant, S.L. FerradalABS 102. POSTNATAL MR-IMAGING AND ADC MEASURES IN CONGENTIAL CYTOMEGALOVIRUS INFEC­TION PROVIDE AN ADDED DIAGNOSTIC VALUE ON CEREBRAL ULTRASOUND IN CHARACTERIZING WHITE MATTER DISEASE • C. Martins, J. Schneider, M. Bickle Graz, M. Kobas, S. Asner, A.C. TruttmannABS 103. COMPARISON OF 1-DIMENSIONAL AND 2-DIMENSIONAL SONOGRAPHIC (US) AND MRI MEASUREMENTS OF THE CEREBELLUM IN TERM NEWBORNS • B. Reulecke, R. Fernandez, M. Mills, V. Pelling, H. Rabe, L. HarrisABS 104. MILD HYPOXIC ISCHAEMIC EN­CEPHA­LOPA­THY AND LONG TERM NEURO­DE­VEL­OP­MENTAL OUTCOME-A SYSTEMATIC REVIEW • J. Conway, B.H. Walsh, M. Dozier, G.B. Boylan, D.M. MurrayABS 105. NEURODEVELOPMENTAL AND SENSORY OUTCOME AT TWO YEARS IN VLBW BABIES: CORRELATIONS WITH BRAIN LESIONS DETECTED AT TERM MRI • M. Malova, L. Ceschi, C. Traggiai, S. Uccella, A. Parodi, A. Sannia, L. Boeri, E. De Grandis, M. Severino, G. Morana, D. Tortora, M.G. Calevo, A. Rossi, E. Veneselli, C. Bellini, L.A. RamenghiABS 106. PREVALENCE OF AUTISM IN EXTREME PRETERM CHILDREN BORN IN STOCKHOLM 2004-2007 • E. Eklof, A. Hedfors Moretti, H. Lagercrantz, S. Bolte, U. AdenABS 107. CEREBRAL AUTOREGULATION IN AS­PHYXI­ATED NEONATES TREATED WITH HYPOTHERMIA • A. Hendriksen, L. Dix, W. Baerts, F. van Bel, F. Groenendaal, P. LemmersABS 108. HYPERECHOGENICITY OF THE LENTICULO­STRIATE ARTERIES: INCIDENCE AND CLINICAL IMPACT IN A TERTIARY NICU • P. Triantafyllidou, M. Papadopoulou, S. Gantseva-Patsoura, F. Kokkori, E. Varxalama, M. Theodoraki, A. GounarisABS 109. A MIXED LIPID EMULSION – RICH IN DOCOSAHEXAENOIC ACID (DHA) – AND ITS EFFECT ON BRAIN MATURATION IN EXTREMELY LOW BIRTH WEIGHT INFANTS • C. Binder, A. Repa, V. Giordano, M. Thanhaeuser, A. Kreissl, N. Haiden, A. Berger, N. Longford, K. Klebermass-SchrehofABS 110. IMPACT OF PARTURITION ON MATERNAL NEURONAL INTEGRITY • K.S. Evers, S. Fouzas, C. Barro, J. Kuhle, U. Fisch, O. Lapaire, S. WellmannABS 111. THE EFFECT OF MORPHINE ON EARLY BRAIN ACTIVITY IN EXTREMELY PRETERM INFANTS: AN OBSERVATIONAL MULTICENTER STUDY • M.L. Tataranno, L.S. de Vries, L. Hellström-Westas, O. Dammann, M. Toet, F. Groenendaal, N.H.P. Claessens, V. Fellman, K. Sävman, M.J.N.L. BendersABS 112. PERSISTENT MONOCYTE AND NEUTROPHIL ACTIVATION IN SCHOOL AGE CHILDREN POST NEONATAL ENCEPHALOPATHY • Z. Zareen, V. Mc Eneaney, N.A. Taher, L. Kelly, D. Sweetman, D. Doherty, E. MolloyABS 113. BLOOD BASED PROTEINS THAT DIFFERENTIATE INFLAMMATION-SENSITIZED HYPOXIA VERSUS HYPOXIA ALONE WITHIN THE 6 H THERAPEUTIC WINDOW IN A PIGLET MODEL • I. Lingam, A. Avdic-Belltheus, K. Martinello, C. Meehan, S. Ragab, I. Tachtsidis, C. Tann, M. Hristova, B. Fleiss, T. Wolfs, B. Kramer, N. Klein, H. Hagberg, P. Gressens, N.J. RobertsonABS 114. BLOOD PLASMA PROFILE OF TEMPORAL MICRORNA EXPRESSION OF INFLAMMATION IN LIPOPOLYSACCHARIDE SENSITISED PORCINE MODEL OF HYPOXIC ISCHAEMIC ENCEPHALOPATHY • A. Avdic-Belltheus, I. Lingam, C. Meehan, K. Martinello, S. Ragab, I. Tachtsidis, C. Tann, M. Hristova, B. Fleiss, T. Wolfs, B. Kramer, N. Klein, H. Hagberg, P. Gressens, N.J. RobertsonABS 115. ARE THE 2 YEAR GRIFFITHS SCORES OF BABIES WITH CEREBELLAR HAEMORRHAGE (CBH) AND INTRAVENTRICULAR HAEMORRHAGE (IVH) SIGNIFICANTLY DIFFERENT COMPARED TO THOSE OF BABIES SUFFERING FROM ISOLATED IVH? • S. Uccella, A. Parodi, M. Malova, L. Boeri, E. De Grandis, C. Traggiai, A. Sannia, M. Severino, G. Morana, D. Tortora, A. Rossi, E. Veneselli, L.A. RamenghiABS 116. INCIDENCE AND CHARACTERISTICS OF INFANTS WITH RETINOPATHY OF PRE­MATURITY IN CROATIA • M. Vucinovic, L.J. Znaor, A. VucinovicABS 117. SYSTEMIC ALTERATIONS IN HYPOXIA-INDUCIBLE FACTOR 1a EXPRESSION AND THE NLRP3 INFLAMMASOME IN POST NEONATAL ENCEPHALOPATHY IN SCHOOL AGE CHILDREN AND RESPONSE TO MELATONIN IN VITRO • L. Russo, V. Mc Eneaney, Z. Zareen, L.A. Kelly, E.J. MolloyABS 118. BRAIN GROWTH AND RELATIONSHIPS WITH ILLNESSES AND NEURODEVELOPMENT OUT­COME • R. D’Ascenzo, B. Pieroni, A. Pianesi, A. Peretti, L. Regnicolo, G. Polonara, M.J. Benders, V.P. Carnielli