SUMMARY
In experiments on rats it was found that the administration of phenylhydrazine in doses of 10 mg, 50 mg and 100 mg / kg of body weight accompanied by a dose-dependent morphological damage of the kidneys. By comparing the morphological disorders in kidneys of rats were used for drinking tap water, 1% NaCl solution or a 0.75% NaCl and 0,36% NaHCO3 found that brines possess nephroprotective activity. The greatest protective effect with respect to kidney toxicity with phenylhydrazine possessed solution containing chloride and sodium bicarbonate.