SUMMARY
Manasova Gulsym, Zelinsky Alexandr, Derishov Sergei, Kuzmina Natalia. ? ??????? ?????????????? ????????????? ?? ???????-????????? ????????? ? ??????????? ????????? ??????? ????? ? ?????????? = About influence of the perinatal infection on calcium-phosphorus homeostasis and structural condition of bone tissue in pregnant women. Journal of Education, Health and Sport. 2016;6(4):271-280. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.50199http://ojs.ukw.edu.pl/index.php/johs/article/view/3470 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 755 (23.12.2015).755 Journal of Education, Health and Sport eISSN 2391-8306 7© The Author (s) 2016;This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, PolandOpen Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium,provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License(http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercialuse, distribution and reproduction in any medium, provided the work is properly cited.The authors declare that there is no conflict of interests regarding the publication of this paper.Received: 20.03.2016. Revised 17.04.2016. Accepted: 17.04.2016. ??? 618.33-022.7-06: 616.71-008.92 ? ??????? ?????????????? ????????????? ?? ???????-????????? ????????? ? ??????????? ????????? ??????? ????? ? ?????????? 1?. ?. ????????, 2?. ?. ?????????, 2?. ?. ???????, 3?. ?. ???????? 1????????? ??????????? ???????????????, ??????2???????? ???????????? ??????????? ???????????3?? «????????? ??? ?5», ?. ?????? ???????? ?????? ???????????? ?????????? ???????????? ???????-?????????? ?????????? ? ?????????? ? ???????????????? ????????????? ?????????????? (???) ? ??????????????? ?????????. ????????? ? ??????. ? ???????? ???????????3 ?????? ??????????: ? ??? ? ???????????? ?/??? ??????????????? ??????????? ???????? (I-A – 192 ?????????), ? ??? ? ??? ?????-???? ?????????? ???????? (I-? - 43); 128 ???????? ?????? ????? ? ?????? ???????? (II). ?????????? ?????? (??) ? ??????????????? ??????? (?? ++), ??????? ? ????? ? ????????? ?? ? ????? ???????????? ??????????????? ???????; ????????? ??????? ????? – ??????? ?????????????? ?????????????. ?????????? ????????????. ???????? ???????? ???????????? ?????? ? ??????????????? ??????? ?? ???? ?????????? ????? ???????????? ? ???????? ((1,89 ± 0,03) ? (1,67 ± 0,05) ?????/?) ? ??????????? ((2,41 ± 0,02) ?? 2-?, (2,16 ± 0,03)- ? 3-?? ?????????? (? < 0,001)) ???????; ? ???????? ?????? ??????? ??????? ????????? ? ???????? ??????????????? ????????????, ???? ??? ??? ??? ???????? ??? ??????????? ???? ???????????? ?? ??????? ?????????. ????????? ???? ? 9,78% ?????????? ? ??? ??????????????? ??????????? ??? ??? ????????? ????????????, ? ? 71,91% - ???????????????? ???????? (???). ? ?????? ???????? ??? ??? ??????? ?????? ? 23,43% ?????????. ??????. ???????????? ??????? ? ????? ?? ???? ?????????? ????? ???????? ??????????????? ????????? ? ? ???????? ?????????? ? ? ?????????? ? ???; ??? ????????????? ??? ??????? ?????????? ????. ????????, ????????? ??????????? ????????? ?????????? ? ??????? ??? ????????????? ?? ?????????????? ???????????????? ??????????? ?????????, ???????????? ??? ???????? ??????. ???????? ???? ??? ??? ??????????????? ????? ??????????? ? ????? ???????? ??????? ????????? ?? ????????? ? ???????????? ???????????? ? ?????? ? ???????? ??????????. ????????????? ????????????? ???????? ????? ?? ???????? ????? ???????? ??????????? ? ??????????.???????? ?????: ????????????, ??????? ?????, ???????-????????? ?????????, ?????????????. About influence of the perinatal infection on calcium-phosphorus homeostasis and structural condition of bone tissue in pregnant women 1Gulsym Manasova, 2Alexandr Zelinsky, 2Sergei Derishov, 3Natalia Kuzmina 1Health Department of the City Council Odessa2Odessa National Medical University, the Medical Faculty3Communal Health Protection Institution “Maternity Hospital ?5”, Odessa, Ukraine ?bstractThe article presents the results of calcium-phosphorus homeostasis study in pregnant women with verified perinatal infection (VPI) and osteopenic syndrome. Materials and methods. 3 groups of pregnant women were examined in dynamics. There were 192 patients with VPI and clinical and/or ultrasound manifestations of infections (I-A), 43 patients had VPI without manifestations of infection (I-B); 128 healthy women constituted the control group (II). The content of general and ionized calcium, phosphorus in blood, and urinarium calcium excretion were defined by photometric method; bone tissue state was examined by ultrasound densitometry. Results. The reduction of total and ionized calcium concentration took place with increasing gestational age ((1,89 ± 0,03) and (1,67 ± 0,05) mmol / l) and control ((2,41 ± 0,02) in the 2nd, (2,16 ± 0,03) - in the 3rd trimester (p <0,001)) groups. Calcium levels in healthy women remained within the physiological concentrations, whereas calcium decrease was significant already in the 2nd trimester at VPI. BMD conformed osteoporosis in 9,78% of the women under observation with the VPI already at the initial examination and osteopenic syndrome (OPS) was identified in 71,91% of women. In the control group OPS was diagnosed in only 23,43% of the patients. Conclusions. Blood calcium concentration is characterized by decrease and depends on increasing gestational age in all groups; calcium level is significantly lower at infected patients. Evidently, elevation of VPI pregnant women calcium needs is not compensated by the mechanisms of physiological adaptation, as against healthy women. Reduced of bone mineral density at infected womwn is characterized by more pronounced and rapid changes in comparison with the same indexes in the group of healthy pregnant women. Perinatal infection is one of risk factor for osteoporosis development in pregnant women.Key words. pregnancy, bone tissue, calcium-phosphorus homeostasis, infection.