SUMMARY
Koshelnik E. L., Desyatsky V. V. ?????????????? ???????? ???????? ??????????? ? ????? ?? ????????????????? ???? = Rats’ experimental acute pancreatitis pharmacological correction. Journal of Education, Health and Sport. 2015;5(10):199-206. ISSN 2391-8306. DOIhttp://dx.doi.org/10.5281/zenodo.32619http://ojs.ukw.edu.pl/index.php/johs/article/view/2015%3B5%2810%29%3A199-206https://pbn.nauka.gov.pl/works/661564Formerly Journal of Health Sciences. ISSN 1429-9623 / 2300-665X. Archives 2011–2014http://journal.rsw.edu.pl/index.php/JHS/issue/archive Deklaracja.Specyfika i zawartosc merytoryczna czasopisma nie ulega zmianie.Zgodnie z informacja MNiSW z dnia 2 czerwca 2014 r., ze w roku 2014 nie bedzie przeprowadzana ocena czasopism naukowych; czasopismo o zmienionym tytule otrzymuje tyle samo punktów co na wykazie czasopism naukowych z dnia 31 grudnia 2014 r.The journal has had 5 points in Ministry of Science and Higher Education of Poland parametric evaluation. Part B item 1089. (31.12.2014).© The Author (s) 2015;This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland and Radom University in Radom, PolandOpen Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium,provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License(http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non commercialuse, distribution and reproduction in any medium, provided the work is properly cited.The authors declare that there is no conflict of interests regarding the publication of this paper.Received: 05.08.2015. Revised 05.09.2015. Accepted: 20.10.2015. ??? 591.437:616.37-002-08 ?????????????? ???????? ???????? ??????????? ? ????? ?? ????????????????? ????RATS’ EXPERIMENTAL ACUTE PANCREATITIS PHARMACOLOGICAL CORRECTION ?. ?. ?????????, ?. ?. ??????????E. L. Koshelnik, V. V. Desyatsky ???????? ???????????? ???????? ???????????, ????? Odessa National Medical University, Odessa SummaryWork is dedicated to model of acute pancreatitis and pathological changes of pancreatic tissues of rats with L-arginine-induced acute experimental pancreatitis and morphological tests of therapeutic effects of different forms of dalargin The obtained data indicate that using of free and liposomal forms of dalargin, with therapeutic aims, in conditions of results in processes of macro- and microscopic changes in pancreatic tissue normalization. Efficacy significantly prevails the same of peptide’s free form. This positive effect is the experimental background in clinical use of nitric oxide blocking and liposomal form of dalargin for treatment of acute pancreatitis.Key words: model, acute experimental pancreatitis, morphology, treatment. ???????????? ?????????? ??????????? ?? ???????? ???????????? ???? ??????? ???????????? ?????? ? ????? ? L-???????-??????????? ??????? ????????????????? ????????????, ? ????? ?????????????? ?????????? ??????????? ??????? ?????? ???? ????????? ?? NG-?????-L-???????? ?? ??? ????. ????????, ?? ?? ???? ???????????????? ???? ?????? ???, ???????????? ?? ????????? ?????????? ??'????? L-????????, ? ??????? ?? ?????????? ???????????? ?????, ?? ?????????? ??? ???????? ????????????? ???????: ?????????, ?????????, ??????. ?? ??????????? ???????????? ???????????? ???? ?????? ???????????? ?????????? ?????.???????????? ??????? ?? ????????????? ???? ????????? ??? L-???????-???????????? ??? ????? ?????? ???????????? ?????- ?? ?????????????? ???? ? ???????? ??. ??? ????? ???????????? ????????????? ????? ????????? ? 1,5 ???? ???????????? ???? ? ??????? ????? ???????. ???????? ???? ? ????????????????? ?????????????? ????????? ?????????? ???????????? ??????????? ??????? ????? ????? ?? ????????????? ???? ????????? ???????? ? ????? ????????? ???????? ???????????.??????? ?????: ??????, ??????? ????????????????? ??????????, ??????????, ?????????. ???????????? ????????? ???????? ?????????????? ????????? ????? ????????????? ?????? ???? ? L-???????-?????????????? ?????? ????????????????? ????????????, ? ????? ???????????????? ???????????? ???????? ???????? ????????? ???? ????????? ? NG-?????-L-????????. ????????, ??? ? ???????? ?????????????? ???? ?????? ???, ??????????????? ?????????? ????????? L-????????, ? ?????? ????????????? ?????? ??????????? ?????????, ??????????? ??? ??????? ??????????????? ????????: ??????????, ??????????, ??????. ??? ???????????? ???????????? ?????????????? ???? ?????? ???????????????? ???????????? ?????????.????????????? ????????? ? ????????????? ???? ????????? ????? ???????????? ???????????? ?????- ? ???????????????? ????????? ????? ??. ??? ???? ????????????? ????????????? ????? ????????? ? 1,5 ???? ????????? ??????? ? ????????? ????? ???????. ?????????? ?????? ???????? ????????????????? ???????????? ???????????????? ????????????? ??????????? ??????? ?????? ????? ? ????????????? ???? ????????? ???????? ? ???????? ???????????? ??? ?????? ??????????? ? ???????.???????? ?????: ??????, L-???????, ?????? ????????????????? ??????????, ??????????, ???????.